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ctla 4 ig  (Bio X Cell)

 
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    Bio X Cell ctla 4 ig
    Ctla 4 Ig, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ctla 4 ig/product/Bio X Cell
    Average 94 stars, based on 15 article reviews
    ctla 4 ig - by Bioz Stars, 2026-03
    94/100 stars

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    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of <t>CTLA4-Ig</t> plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .
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    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of <t>CTLA4-Ig</t> plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .
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    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of <t>CTLA4-Ig</t> plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .
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    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of <t>CTLA4-Ig</t> plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .
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    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of <t>CTLA4-Ig</t> plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .
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    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of <t>CTLA4-Ig</t> plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .
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    Image Search Results


    (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .

    Journal: Cell reports

    Article Title: Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling

    doi: 10.1016/j.celrep.2024.114664

    Figure Lengend Snippet: (A) Schematic of the experimental setup. (B) Determination of blood half-life time of 89 Zr-NB ( n = 5 mice/group). (C) Representative whole-body 2D positron emission tomography with computed tomography (PET/CT) image of a C57BL/6J mouse heterotopically transplanted with a BALB/c heart 24 h after injection of 89 Zr-NBs. (D) Gamma counting of organs from C57BL/6J mice heterotopically transplanted with a BALB/c heart 24 h after 89 Zr-NBs injection ( n = 5 mice/group). (E) Flow cytometry of DiO-NB uptake in bone marrow, spleen, and graft 24 h after DiO-NB administration ( n = 3 mice/group). (F) Kaplan-Meier curve with log-rank test for graft survival ( n = 6 mice/group). *** p < 0.001. (G) Leukocytes infiltrated in native hearts and allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated mice 100 days post-transplantation ( n = 6 mice). * p < 0.05, paired t test. (H) Immune cell subsets in allografts of CTLA4-Ig plus CD40-TRAF6i-NB-treated recipient mice 100 days post-transplantation ( n = 6 mice). Mean ± SEM are shown. See also and .

    Article Snippet: InVivoMAb Recombinant CTLA4-Ig (for in vitro studies) , BioXcell , Cat#BE0099; RRID: AB_10949064.

    Techniques: Positron Emission Tomography, Computed Tomography, Positron Emission Tomography-Computed Tomography, Injection, Flow Cytometry, Transplantation Assay

    KEY RESOURCES TABLE

    Journal: Cell reports

    Article Title: Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling

    doi: 10.1016/j.celrep.2024.114664

    Figure Lengend Snippet: KEY RESOURCES TABLE

    Article Snippet: InVivoMAb Recombinant CTLA4-Ig (for in vitro studies) , BioXcell , Cat#BE0099; RRID: AB_10949064.

    Techniques: Purification, Recombinant, In Vitro, Staining, Protease Inhibitor, In Vivo, Enzyme-linked Immunosorbent Assay, Cell Isolation, Isolation, CyQUANT Assay, LDH Cytotoxicity Assay, Chromatin Immunoprecipitation, Functional Assay, Software